Adverse Effects Seen in Immunologically Compromised Hosts

Unraveling Immunological Intricacies: Adverse Effects in Hosts
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ADVERSE EFFECTS SEEN IN IMMUNOLOGICALLY COMPROMISED HOSTS

Introduction to the theme of adverse effects in immunologically compromised hosts.


Adverse effects of viral vaccines

Discussion of negative consequences resulting from viral vaccines.

Seen in normal hosts

Observation that these adverse effects are typically found in individuals with normal immune systems.

The pathogenesis of which is unclear

Uncertainty about the cause or development of these effects, specifically related to the pathogenesis.

But which is thought to have an

Suggesting that the cause might have an immunologic foundation.

Immunologic basis

Further emphasis on the role of the immune system in adverse effects.


Postinfectious or postvaccinal

Discussion of adverse effects occurring after infection or vaccination.

Encephalomyelitis is the classic example

Highlighting encephalomyelitis as a classic example of a disease resulting from cell-mediated hypersensitivity.

Of a disease mediated by cell-mediated

Pointing out that the mentioned disease is mediated by cell-mediated hypersensitivity.

Hypersensivity

Specifically identifying cell-mediated hypersensitivity as the mechanism.


These children fail to develop the rash

Noting a failure in the development of the typical rash associated with measles in affected children.

Of measles and specific measles

Mentioning the absence of specific antibodies against measles.

Neutralizine antibody and subsequently die

Describing a dire consequence – death – as a result of the failure to develop specific antibodies.


Adverse effects of vaccines seen

Reiterating adverse effects related to vaccines in individuals with normal immune systems.

In normal hosts that appear to be

Indicating that these effects seem connected to the nature of the antigen or the method of administration.

Related to the nature of the

Implying that the nature of the antigen plays a role in adverse effects.

Antigen or the route of administration

Suggesting that the route of administration may also influence adverse effects.

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